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CHAPTER 3
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Table 3.3 Correlations between hippocampal global and subfield volumes and severity of dissociative symptoms or childhood traumatizing events in the patients Partial correlation r(P-value)1
Global volume
Left hippocampus Right hippocampus
-0.11 (0.57) -0.20 (0.29)
-0.20 (0.29) -0.22 (0.23)
-0.49 (0.006*) -0.39 (0.038*)
-0.38 (0.039*) -0.37 (0.051^)
-0.32 (0.094^)
-0.24 (0.22) -0.27 (0.16)
-0.43 (0.020*) -0.44 (0.018*)
-0.33 (0.020*) -0.41 (0.026*)
Subfield volumes
Left CA1
Right CA1
Left CA2-3
Right CA2-3
Left CA4-DG
Right CA4-DG
Left presubiculum
-0.26 (0.15) -0.15 (0.43) -0.21 (0.25) -0.14 (0.44) -0.25 (0.17) -0.09 (0.63) -0.39 (0.031*)
-0.15 (0.42) 0.001 (0.99) -0.20 (0.28) 0.05 (0.79) -0.25 (0.17) -0.05 (0.77) -0.49 (0.005*)
-0.30 (0.11)
-0.13 (0.49) -0.25 (0.19) -0.19 (0.32) -0.30 (0.11) -0.26 (0.16) -0.27 (0.15) -0.60 (0.001*)
-0.25 (0.19)
-0.22 (0.24) -0.05 (0.79) -0.24 (0.20) -0.15 (0.45) -0.31 (0.10^) -0.13 (0.50) -0.59 (0.001*)
-0.41 (0.029*) -0.25 (0.19) -0.44 (0.018*) -0.35 (0.059^) -0.42 (0.022*) -0.30 (0.12) -0.54 (0.003*)
-0.32 (0.094^)
Right presubiculum Left subiculum Right subiculum Left fimbria
0.02 (0.90) -0.37 (0.040*) -0.17 (0.35) -0.03 (0.87) 0.20 (0.27)
-0.21 (0.25) -0.31 (0.086^) -0.19 (0.31) 0.20 (0.28) 0.19 (0.31)
-0.13 (0.51) -0.46 (0.013*) -0.33 (0.081^) -0.06 (0.72) 0.10 (0.96)
-0.17 (0.37) -0.38 (0.041*) -0.31 (0.11) 0.006 (0.98) 0.17 (0.37)
-0.27 (0.15) -0.45 (0.013*) -0.21 (0.26) 0.02 (0.90) 0.08 (0.69)
-0.26 (0.18) -0.46 (0.013*) -0.12 (0.52) 0.01 (0.95) 0.09 (0.63)
-0.14 (0.45) -0.56 (0.001*) -0.35 (0.060^) 0.004 (0.98) 0.14 (0.45)
-0.22 (0.24) -0.54 (0.002*) -0.31 (0.10^) -0.002 (0.99) 0.12 (0.54)
Right fimbria
Abbreviations:
DES
SDQ-20
Childhood trauma questionnaire (CTQ)
emotional neglect
physical neglect
emotional abuse
physical abuse
sexual abuse
Total trauma
-0.25 (0.18) -0.35 (0.064^) -0.34 (0.069^) -0.37 (0.051^) -0.29 (0.12) -0.46 (0.012*)
-0.12 (0.54) -0.36 (0.057^) -0.27 (0.15) -0.38 (0.044*) -0.25 (0.18) -0.56 (0.002*)
-0.21 (0.27)
CTQ= childhood trauma questionnaire; DES= dissociative experience scale; SDQ= somatoform dissociative questionnaire; PTSD= posttraumatic stress disorder; 1 Controlled for age and parenchymal volume; * P-value ≤ 0.05; ^ 0.05 < P-value ≤ 0.1 (a trend)
-0. 32 (0.093^)
-0.38 (0.044*)
-0.33 (0.081^)
-0.41 (0.027*)
-0.29 (0.13)
-0.64 (<0.001*)