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HIPPOCAMPAL MORPOHLOGY AND CHILDHOOD TRAUMA
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Table 3.1 Demographic and clinical characteristics of the participants All-PTSD to HC comparison
Different group comparisons
Clinical measures
Dissociative symptoms
Psychoform (DES) Somatoform (SDQ-20)
38.79 (22.09) 45.24 (19.65)
5.02 (3.10) 22.04 (2.21)
<0.001* <0.001*
54.41 (16.18) 57.06 (17.26)
22.18 (13.83) 32.69 (13.43)
<0.001* <0.001*
<0.001* <0.001*
<0.001* <0.001*
Traumatic experience checklist (TEC)
Total lifetime trauma 14.40 (5.16) Childhood Trauma Questionnaire (CTQ)2
1.96 (1.93)
<0.001*
17.53 (4.08)
11.06 (4.01)
<0.001*
<0.001*
<0.001*
emotional neglect physical neglect emotional abuse physical abuse sexual abuse Total trauma
19.90 (5.69) 13.87 (5.22) 18.48 (6.56) 12.35 (5.94) 13.84 (7.69) 78.45 (26.92)
10.36(4.14) 7.42 (2.28) 7.50 (2.56) 5.43 (1.34) 5.29 (0.73) 36.00 (8.00)
<0.001* <0.001* <0.001* <0.001* <0.001* <0.001*
23.40 (2.26) 17.47 (3.87) 22.80 (3.30) 15.60 (5.37) 17.87 (7.32) 97.13 (16.63)
16.63 (6.02) 10.50 (3.93) 14.44 (6.31) 9.31 (4.84) 10.06 (6.06) 60.94 (22.70)
<0.001* <0.001* <0.001* <0.001* <0.001* <0.001*
<0.001* <0.001* <0.001* <0.001* <0.001* <0.001*
<0.001* 0.020* <0.001* 0.018* 0.024* <0.001*
Abbreviations:
Mean (SD) All-PTSD (n=33)
t-test: P Value
Mean (SD)
t-test: P Value PTSD-DID PTSD-DID PTSD-only
HC (n=28)
All-PTSD vs. HC
PTSD-DID (n=17)
PTSD-only (n=16)
vs. HC
vs. PTSD- only
vs. HC
PTSD-only= patients with only posttraumatic stress disorder; PTSD-DID= patients with PTSD and dissociative identity disorder; All-PTSD= includes both PTSD-only and PTSD-DID patient groups. HC= healthy controls; 1 one PTSD-DID patient used typical antipsychotics in the past but stopped and was using atypical antipsychotics at the time of the MRI scan. Another PTSD-DID patient was using atypical antipsychotics in the past but was not using any antipsychotics at the time of the MRI scan.
2 CTQ data was available for 15 PTSD-DID, 16 PTSD-only and 14 HC; * P-value<=0.05