Page 59 - Cardiac abnormalities after aneurysmal subarachnoid hemorrhage

Time course and risk factors for myocardial dysfunction after aSAH
Statistical analysis:
Baseline characteristics were analyzed using descriptive statistics. WMSI was dichotomized on one standard deviation above the median.WMA were divided in early WMA, which were present on admission and late WMA, which were present on the echocardiograms on day 4 and/or day 8 after the onset of the aSAH but with a normal admission echocardiogram. Univariable odds ratios (OR) with corresponding 95% confidence intervals (CI) were calculated using logistic regression for baseline determinants and early and late WMA. For determinant-outcome combinations that yielded a significance level of 5% in the univariable analysis, multivariable adjustments were performed. Missing values were excluded by casewise deletion. Hijdra score was dichotomized on the median. Because rebleeding of the aneurysm may cause late WMA we performed a sensitivity analysis with exclusion of patients with a rebleed.
Results: 4
Participants:
Three hundred and twenty patients were assessed for eligibility. Five patients were not included because no aneurysm was found; for 5 others informed consent was declined by next of kin. Nine were excluded: in 6 no cardiac examination could be performed and 3 were lost to follow-up. Three hundred and one patients with aSAH were included and underwent the cardiac examinations. Table 1 shows the baseline characteristics.
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