Page 97 - Slipped Capital Femoral Epiphysis Pathogenetic and Clinical aspects

and control physes looked similar with the markers in this study, the molecular composition of either matrix or within cells may have been very different.
Table 4
Morphological findings in growth plates accompanying SCFE, literature review
First 5 Studies also mentioned presence of repair tissue and affirmed presence of slip in the hypertrophic
zone. 5
Conclusion
SCFE generally shows a perturbed architecture of the regular aligned structures in the physis but the normal phenotype of hypertrophic chondrocytes prevail. Neither alteration in apoptosis nor in vessel density could be found, and no differences were observed in hormonal receptor expression of eight hormonal receptors which are important in puberty.
Based on our study, biomechanical seem more likely than biochemical factors as a cause of SCFE.
Slipped Capital Femoral Epiphysis
article
N=
Resting zone N=normal A=abnormal
Disorientation columnar structure
D: in hypertrophic and proliferative zone:
W: widened hypertrophic zone.
Intracellular abnormalities N=normal A+abnormal;
Extracellular matrix N=normal A=abnormal
1977[17] 3 (1) 1985[2, 3] 23 1989[12] 6 2003[11] 18 2005[1] 3 2009[21] 9 2010[10] 6
N D
ND N/A
(W) N A (W) A D AA
N D D D D
N A
A
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