Page 61 - The diagnostic work-up of women with postmenopausal bleeding
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Table 2. Predictor variables evaluated and used in the prediction models
2
1
1 1
2 3 3
1
3 3 3
2
2
1 1 1
1
3
3 1
1 3
1 2 3
3 1
Prediction models
Patient history variables
Age
BMI
Diabetes 3 Frequency of bleeding
Amount of bleeding
HRT use 1 1 Anticoagulant use
Nulliparity
Time since menopause 3
VAS-score
Examiner 3
Hyper tension 3 Thyroid dysfunction
History of cancer
Endometrial thickness 1 1 1 Heterogeneous echogenicity/morphology 1 1 Endometrial border 1 Endometrial fluid in cavity 3 Endometrial area 2
Vascularised area 2 Endometrial colour score 1 Irregular branching
Vascularity index 1 Mean intensity of pixels in endometrial area 2 Mean intensity of pixels in vascularised area 3
Suspicious hysteroscopy findings 1
321112111 3 1 113
1 113 1 1
1
1
1
1
2
Ultrasound variables – grey-scale
Ultrasound variables – Doppler
Hysteroscopy variables
1 = statistically significant in multivariate analysis and included in model
2 = statistically significant in univariate analysis and not included in model 3 = not statistically significant and not included in prediction model
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Epstein 2002 Randelzhofer 2002 Bachmann 2003 Bruchim 2004 Opmeer 2006 Opolskiene 2007 Burbos 2010 Burbos 2011 Opolskiene 2011