Page 194 - Characterization of genetic neurodevelopmental disorders at adult age, with a focus on 22q11.2 deletion syndrome - Emma Boersma
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Chapter 7
Abstract
22q11.2 deletion syndrome (22q11.2DS) is associated with an elevated
genetic risk of several psychiatric disorders. The prevalence of post-
traumatic stress disorder (PTSD) has however been reported to be only
0.9%; lower compared to the general population. We explored occurrence of
PTSD and traumatic events in a Dutch cohort of 112 adults with 22q11.2DS.
PTSD was reported in 8.0%, traumatic events in 20.5%, and trauma-focused
treatment in 17.9% of patients. Our novel findings suggest PTSD may be
underdiagnosed in 22q11.2DS. Clinicians and other caregivers should be
alert to trauma in this population in order to enable treatment and minimize
psychiatric burden.
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