Page 106 - Cardiac abnormalities after aneurysmal subarachnoid hemorrhage
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Chapter 7
of nucleotides receptors (for example the ATP receptor P2X7 or the ADP receptor P2Y12) and the inhibition of the different nucleotide ecto-enzymes which leads to a decrease in tissue adenosine level may prevent or decrease the cardiac abnormalities after aSAH and perhaps also in ischemic stunning. Finally, further insights in the catecholaminergic myocarditis which is described in Chapter 6, are needed. By using immunohistochemistry and for example investigating presence of adhesion molecules such as ICAM and VCAM in the myocardium of patients with aSAH, our knowledge on neurogenic myocardial dysfunction will be enriched.
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