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Curriculum Vitae
Jackelien van Scheppingen was born on the 23rd of December, 1988 in Ter Aar, The Netherlands. She received her secondary school degree at the Groene Hart Lyceum in Alphen aan den Rijn in 2007. After one year at the Amsterdam University of the Arts, she started her study Psychobiology at the University of Amsterdam. She performed her bachelor’s internship at the department of Experimental Immunohematology at Sanquin Research in Amsterdam, under supervision of prof. Van Ham, investigating the expression of the neonatal Fc receptor in B cells in humans. She received her bache- lor’s degree in 2011 and continued with the master’s program Biomedical Sciences, track Pyschopharmacology and Pathophysiology at the University of Amsterdam. During this master she did her first internship in prof. Aronica’s group at the department of Neuropathology at the Academic Medical Center in Amsterdam, working on the projects ‘Expression patterns of DR6, APP and caspase 6 in normal development and in Alzheimer’s disease pathology’ and ‘Isolation of neural progenitor cells from fetal tissue and their dif- ferentiation into neurons and astrocytes’. She performed her second internship at the Neuroimmunology group at the Netherlands Institute for Neuroscience in Amsterdam, under supervision of dr. Huitinga, working on the project ‘The functional role of scav- enger receptors in myelin uptake in Multiple Sclerosis’. She finished the master with her thesis ‘The isolation and characterization of primary human astrocytes from adult brain tissue’, supervised by dr. Van Strien at the Netherlands Institute for Neuroscience. She received her master’s degree in January 2014, after which she returned to the depart- ment of Neuropathology at the Academic Medical Center to work as a PhD student. Under supervision of prof. Aronica and dr. Van Vliet she investigated the role of astro- cytes and microRNAs in inflammatory processes in epilepsy, with a focus on tuberous sclerosis complex, of which the results are described in this thesis.
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