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MIR147B: A NOVEL KEY REGULATOR OF IL-1β-MEDIATED INFLAMMATION IN ASTROCYTES
  Supplementary Figure 1 Relationship between C15orf48 and miR147b. The genomic location of C15orf48 and miR147b is shown. Both transcripts are transcribed from the same template strand on chromosome 15. The pre-miR147b transcript is harbored within a region that is also tran- scribed as the 3’ UTR of C15orf48. There was a strong correlation between miR147b and C15orf48 expression levels (ρ=0.96, p-value<0.0001, Spearman’s rank correlation test). Expression is shown in log2(normalized read-counts+1).
Supplementary Figure 2 miR147b expression in tuberous sclerosis complex (TSC) cortical tubers and temporal lobe epilepsy with hippocampal sclerosis (TLE-HS). Quantitative real-time PCR of fresh frozen brain tissue. A miR147b expression levels in TSC tubers (n=16) did not differ to expression in control cortex (n=19), however increased levels are observed in a subset of patients. B expression levels in TLE-HS (n=16) were increased compared to control hippocampus (n=14).
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